BDBM50324475 Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzyl)amide Bis-(trifluoroacetate)::CHEMBL1215083::CHEMBL1229259
SMILES NC(=N)NCCC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N
InChI Key InChIKey=QKFCYPKTTJCUSZ-YADHBBJMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50324475
Affinity DataKi: 1.94nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Inhibition of plasma kallikreinMore data for this Ligand-Target Pair
TargetTransmembrane protease serine 11D(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...More data for this Ligand-Target Pair
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of recombinant catalytic domain of TMPRSS2 expressed in Escherichia coli using Dcyclohexylalanine- Pro-Arg-AMC as substrate by fluorescenc...More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of matriptase 2More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair