BDBM50324796 3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophenyl)propanamide::CHEMBL1221633

SMILES [O-][N+](=O)c1ccc(NC(=O)CCc2cn(Cc3ccc(Cl)cc3)c3ccccc23)cc1

InChI Key InChIKey=JJPXEFKUBDVJJP-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50324796   

TargetVascular endothelial growth factor receptor 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of recombinant KDR after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of recombinant JAK3 after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 3.81E+4nMAssay Description:Inhibition of recombinant YES after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Pim1 after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant c-Abl after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HIPK1 after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant aurora A after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant TrkA after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50324796(3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophe...)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of recombinant JAK2 after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed