BDBM50325184 6-(((3R,4R/3S,4S)-4-(3-(4-Fluoro-3-methylphenoxy)-phenoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine::CHEMBL1222676

SMILES Cc1cc(Oc2cccc(O[C@H]3CNC[C@H]3Cc3cccc(N)n3)c2)ccc1F

InChI Key InChIKey=UMNBPZTVSUHLQZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50325184   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325184(6-(((3R,4R/3S,4S)-4-(3-(4-Fluoro-3-methylphenoxy)-...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325184(6-(((3R,4R/3S,4S)-4-(3-(4-Fluoro-3-methylphenoxy)-...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325184(6-(((3R,4R/3S,4S)-4-(3-(4-Fluoro-3-methylphenoxy)-...)
Affinity DataKi:  7.91E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed