BDBM50325763 1-(2',5'-bis(trifluoromethyl)biphenyl-3-yl)-5-methyl-1H-pyrazole-3-carboxamide::CHEMBL1224195

SMILES Cc1cc(nn1-c1cccc(c1)-c1cc(ccc1C(F)(F)F)C(F)(F)F)C(N)=O

InChI Key InChIKey=KJKVVLUSAUZZBG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325763   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325763(1-(2',5'-bis(trifluoromethyl)biphenyl-3-yl)-5-meth...)
Affinity DataIC50: 272nMAssay Description:Inhibition of human Nav 1.7 channel by voltage-ion-probe-readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325763(1-(2',5'-bis(trifluoromethyl)biphenyl-3-yl)-5-meth...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325763(1-(2',5'-bis(trifluoromethyl)biphenyl-3-yl)-5-meth...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325763(1-(2',5'-bis(trifluoromethyl)biphenyl-3-yl)-5-meth...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed