BDBM50325957 CHEMBL1223887::N-(3-(1-(3-(1-(3-(trifluoromethoxy)benzyl)-1H-benzo[d]imidazol-2-ylamino)propyl)piperidin-4-yl)phenyl)acetamide

SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCNc2nc3ccccc3n2Cc2cccc(OC(F)(F)F)c2)CC1

InChI Key InChIKey=CJMPRNGIJURBAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325957   

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325957(N-(3-(1-(3-(1-(3-(trifluoromethoxy)benzyl)-1H-benz...)
Affinity DataIC50: 88nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHOK1 cells assessed as reduction in [3H]inositol phosphate levels by scintillation proxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325957(N-(3-(1-(3-(1-(3-(trifluoromethoxy)benzyl)-1H-benz...)
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHOK1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed