BDBM50326120 2-[2-(4-Chloro-phenylamino)-4-phenyl-thiazol-5-yl]-3-(4-methoxy-phenyl)-3H quinazolin-4-one::CHEMBL1242519

SMILES COc1ccc(cc1)-n1c(nc2ccccc2c1=O)-c1sc(Nc2ccc(Cl)cc2)nc1-c1ccccc1

InChI Key InChIKey=FSKJBECTGTZULY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326120   

TargetTranscription factor Jun(Human)
B.V. Patel Pharmaceutical Education and Research Development Centre

Curated by ChEMBL
LigandPNGBDBM50326120(2-[2-(4-Chloro-phenylamino)-4-phenyl-thiazol-5-yl]...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed