BDBM50326133 6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,2-d][1,4]oxazine::CHEMBL1242904

SMILES Cc1ccc2c(cccc2n1)N1CCN(CCc2cccc-3c2OCc2nccn-32)CC1

InChI Key InChIKey=LHWYHPOPXMPQGV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326133   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326133(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethy...)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326133(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant CYP2C9 preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326133(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant CYP2C19 preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed