BDBM50326136 1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)ethanone O-methyl oxime::CHEMBL1241737

SMILES CO\N=C(/C)c1ncn-2c1COc1c(CCN3CCN(CC3)c3cccc4nc(C)ccc34)cccc-21

InChI Key InChIKey=QUHVYHRTOAXCMZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326136   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326136(1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)e...)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326136(1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)e...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant CYP2C9 preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326136(1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)e...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant CYP1A2 preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed