BDBM50326379 (2S)-1-({(2S,4S)-4-[2-(5-Trifluoromethyl-1,3-dihydro-2H-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile::CHEMBL1242966

SMILES FC(F)(F)c1ccc2CN(Cc2c1)C(=O)C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=AGDIQXJJZSTMQS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326379   

TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326379((2S)-1-({(2S,4S)-4-[2-(5-Trifluoromethyl-1,3-dihyd...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant FAP expressed in Hi5 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326379((2S)-1-({(2S,4S)-4-[2-(5-Trifluoromethyl-1,3-dihyd...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant His-tagged DPP9 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326379((2S)-1-({(2S,4S)-4-[2-(5-Trifluoromethyl-1,3-dihyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP8 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326379((2S)-1-({(2S,4S)-4-[2-(5-Trifluoromethyl-1,3-dihyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP2 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326379((2S)-1-({(2S,4S)-4-[2-(5-Trifluoromethyl-1,3-dihyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP4 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed