BDBM50326731 (-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL1254947

SMILES CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)C1CCc2c(O)cccc2C1

InChI Key InChIKey=KLFRUTOTKKRLHR-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50326731   

TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50326731((-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(...)
Affinity DataKi:  2.36nMAssay Description:Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50326731((-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(...)
Affinity DataKi:  53.6nMAssay Description:Displacement of [3H]spiperone from rat D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50326731((-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(...)
Affinity DataEC50:  52.6nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50326731((-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(...)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed