BDBM50326911 3-(2,4-Difluorobenzyl)-8-(2,4-difluorophenyl)-1-methylpyrido-[3,2-d]pyridazin-2(1H)-one::CHEMBL1253813

SMILES Cn1c2c(nncc2cc(Cc2ccc(F)cc2F)c1=O)-c1ccc(F)cc1F

InChI Key InChIKey=JBICTACFWPDHRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326911   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50326911(3-(2,4-Difluorobenzyl)-8-(2,4-difluorophenyl)-1-me...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed