BDBM50326924 CHEMBL1254814::N-Cyclopropyl-3-(8-(2-fluoro-4-(trifluoromethyl)phenyl)-1-methyl-2-oxo-1,2-dihydropyrido[3,2-d]pyridazin-3-yl)-4-methylbenzamide

SMILES Cc1cnc(cc1-c1cc2cnnc(-c3ccc(cc3F)C(F)(F)F)c2n(C)c1=O)C(=O)NC1CC1

InChI Key InChIKey=GDXZOJVRIMPLOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326924   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50326924(N-Cyclopropyl-3-(8-(2-fluoro-4-(trifluoromethyl)ph...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed