BDBM50326960 (S)-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl)-2-naphthamide::CHEMBL1254495

SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1cccc(F)c1)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=MNKBFXBSNSUUTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326960   

TargetPhospholipase D1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50326960((S)-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspi...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50326960((S)-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspi...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed