BDBM50327078 1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{4-[(1-methylpiperidin-4-yl)oxy]-3-(trifluoromethyl)phenyl}urea::CHEMBL1254839

SMILES CN1CCC(CC1)Oc1ccc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2Cl)cc1C(F)(F)F

InChI Key InChIKey=NCTRDRAFCRZEPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327078   

TargetVascular endothelial growth factor receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327078(1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataIC50: 12nMAssay Description:Inhibition of His-tagged human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327078(1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataIC50: 270nMAssay Description:Inhibition of His-tagged human FGFR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed