BDBM50327270 CHEMBL1258846::endo-3-(8-(2-phenylpropan-2-yl)-8-azabicyclo[3.2.1]octan-3-yloxy)benzamide

SMILES CC(C)(c1ccccc1)N1[C@@H]2CC[C@H]1C[C@H](Oc1cccc(C(N)=O)c1)C2

InChI Key InChIKey=VSDXEUDHEKJAHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327270   

LigandChemical structure of BindingDB Monomer ID 50327270BDBM50327270(endo-3-(8-(2-phenylpropan-2-yl)-8-azabicyclo[3.2.1...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50327270BDBM50327270(endo-3-(8-(2-phenylpropan-2-yl)-8-azabicyclo[3.2.1...)
Affinity DataIC50: 1.33E+4nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed