BDBM50327277 CHEMBL1257458::endo-3-(8-((R)-1-(6-methylpyridin-3-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yloxy)benzamide

SMILES Cc1ccc([C@@H](C)N2[C@@H]3CC[C@H]2C[C@H](Oc2cccc(C(N)=O)c2)C3)cn1

InChI Key InChIKey=FFCXAJUMJUOFPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327277   

LigandChemical structure of BindingDB Monomer ID 50327277BDBM50327277(endo-3-(8-((R)-1-(6-methylpyridin-3-yl)ethyl)-8-az...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50327277BDBM50327277(endo-3-(8-((R)-1-(6-methylpyridin-3-yl)ethyl)-8-az...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50327277BDBM50327277(endo-3-(8-((R)-1-(6-methylpyridin-3-yl)ethyl)-8-az...)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human mu opioid receptor assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed