BDBM50327375 (1S,2R,5aS,7R,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-hydroxyoctahydrocyclopenta[a]pyrrolizin-5(5aH)-one::CHEMBL1257466

SMILES C[C@@H](O[C@H]1CN2[C@@H]([C@@H]3C[C@@H](O)C[C@@H]3C2=O)[C@@H]1c1ccc(F)cc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=IXAYPVHFYLGKGT-RSKZVPLKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327375   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50327375((1S,2R,5aS,7R,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoro...)
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50327375((1S,2R,5aS,7R,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoro...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in presence of 50% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed