BDBM50327421 1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(4-fluorophenyl)urea::CHEMBL1257840

SMILES Fc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CCOCC2)N2C3CCC2COC3)cc1

InChI Key InChIKey=ZFFYRSOJDYAHTC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327421   

LigandPNGBDBM50327421(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PI3K-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327421(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50327421(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...)
Affinity DataIC50:  154nMAssay Description:Inhibition of PI3K-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed