BDBM50327691 3-fluoro-5-(2-(pyridin-2-yl)-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)benzonitrile::CHEMBL1257395

SMILES Fc1cc(cc(c1)N1CCn2cc(nc2C1)-c1ccccn1)C#N

InChI Key InChIKey=UKROXZGERLZVFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327691   

TargetMetabotropic glutamate receptor 5(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50327691(3-fluoro-5-(2-(pyridin-2-yl)-5,6-dihydroimidazo[1,...)
Affinity DataIC50: 153nMAssay Description:Modulation of human recombinant mGluR5 expressed in CHO cells assessed as inhibition of glutamate-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed