BDBM50327825 1-(1-(2-(4-Benzylpiperazin-1-yl)acetyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea::CHEMBL1257286::US9296693, 50

SMILES FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)CN2CCN(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=JYKYIEPRMTUCEV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327825   

TargetBifunctional epoxide hydrolase 2(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50327825(1-(1-(2-(4-Benzylpiperazin-1-yl)acetyl)piperidin-4...)
Affinity DataIC50:  1.5nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBifunctional epoxide hydrolase 2(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50327825(1-(1-(2-(4-Benzylpiperazin-1-yl)acetyl)piperidin-4...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBifunctional epoxide hydrolase 2(Mouse)
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327825(1-(1-(2-(4-Benzylpiperazin-1-yl)acetyl)piperidin-4...)
Affinity DataIC50:  18nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBifunctional epoxide hydrolase 2(Mouse)
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327825(1-(1-(2-(4-Benzylpiperazin-1-yl)acetyl)piperidin-4...)
Affinity DataIC50:  18nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent