BDBM50327830 1-(3,4-Methylenedioxyphenyl)-3-(1-propionylpiperidin-4-yl)urea::CHEMBL1257989::US9296693, 17

SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc2OCOc2c1

InChI Key InChIKey=HHAWKFZAWJQANW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327830   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50327830BDBM50327830(1-(3,4-Methylenedioxyphenyl)-3-(1-propionylpiperid...)
Affinity DataIC50: 61nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50327830BDBM50327830(1-(3,4-Methylenedioxyphenyl)-3-(1-propionylpiperid...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50327830BDBM50327830(1-(3,4-Methylenedioxyphenyl)-3-(1-propionylpiperid...)
Affinity DataIC50: 100nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Mouse)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50327830BDBM50327830(1-(3,4-Methylenedioxyphenyl)-3-(1-propionylpiperid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed