BDBM50328369 CHEMBL1257558::diethyl 4-(2-fluorophenyl)-2-morpholino-7-propylpyrrolo[1,2-b]pyridazine-5,6-dicarboxylate

SMILES CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(cc(nn12)N1CCOCC1)-c1ccccc1F

InChI Key InChIKey=RILVSDSEWPZKAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328369   

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328369(CHEMBL1257558 | diethyl 4-(2-fluorophenyl)-2-morph...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328369(CHEMBL1257558 | diethyl 4-(2-fluorophenyl)-2-morph...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed