BDBM50328505 (R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrodibenzo[b,f]thiepin-2-yl)methyl)isobutyramide::CHEMBL1259189

SMILES CC(C)C(=O)NCc1ccc2Sc3ccccc3C[C@@H](N3CCN(C)CC3)c2c1

InChI Key InChIKey=SHVCHMGRIYXVAY-OAQYLSRUSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50328505   

TargetAlpha-1B adrenergic receptor(Golden hamster)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328505((R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Bovine)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328505((R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]prozosin from bovine cloned alpha1a receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328505((R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H1 receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328505((R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]prozosin from human cloned histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328505((R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]prozosin from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328505((R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed