BDBM50328880 CHEMBL1271174::N-benzyl-3-(2-cyano-6-propylpyrimidin-4-yl)-N-methyl-5-(trifluoromethyl)benzamide

SMILES CCCc1cc(nc(n1)C#N)-c1cc(cc(c1)C(F)(F)F)C(=O)N(C)Cc1ccccc1

InChI Key InChIKey=MQWFPEJVMZVZBQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328880   

TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328880(N-benzyl-3-(2-cyano-6-propylpyrimidin-4-yl)-N-meth...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant cathepsin K using Z-Phe-Arg-MCA substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328880(N-benzyl-3-(2-cyano-6-propylpyrimidin-4-yl)-N-meth...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H] dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed