BDBM50328925 (3S,4R)-4-(6-((3-(2-chloro-3,6-difluorophenyl)-2,3-dihydroisoxazol-5-yl)methoxy)pyridin-3-yl)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cyclopropyl-4-hydroxypiperidine-3-carboxamide::CHEMBL1269762

SMILES COCCc1ccc(Cl)c(CN(C2CC2)C(=O)[C@H]2CNCC[C@]2(O)c2ccc(OCC3=CC(NO3)c3c(F)ccc(F)c3Cl)nc2)c1

InChI Key InChIKey=LDOOJWYIGGXIHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328925   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328925((3S,4R)-4-(6-((3-(2-chloro-3,6-difluorophenyl)-2,3...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328925((3S,4R)-4-(6-((3-(2-chloro-3,6-difluorophenyl)-2,3...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed