BDBM50329067 CHEMBL1271288::N2-(3,5-dimorpholinophenyl)-N4-(1H-indol-4-yl)pyrimidine-2,4-diamine

SMILES C1CN(CCO1)c1cc(Nc2nccc(Nc3cccc4[nH]ccc34)n2)cc(c1)N1CCOCC1

InChI Key InChIKey=WZSPEUXTQGLMHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329067   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329067(N2-(3,5-dimorpholinophenyl)-N4-(1H-indol-4-yl)pyri...)
Affinity DataIC50: 117nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329067(N2-(3,5-dimorpholinophenyl)-N4-(1H-indol-4-yl)pyri...)
Affinity DataIC50: 856nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed