BDBM50329477 (S)-N-(3-(4-(3-aminopropylamino)butylamino)propyl)-3-cyclohexyl-2-(2-(naphthalen-1-yl)acetamido)propanamide::CHEMBL1269126

SMILES NCCCNCCCCNCCCNC(=O)[C@H](CC1CCCCC1)NC(=O)Cc1cccc2ccccc12

InChI Key InChIKey=BKXZRLFPGYWHTM-LJAQVGFWSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329477   

TargetMetabotropic glutamate receptor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50329477((S)-N-(3-(4-(3-aminopropylamino)butylamino)propyl)...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50329477((S)-N-(3-(4-(3-aminopropylamino)butylamino)propyl)...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at alpha4beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50329477((S)-N-(3-(4-(3-aminopropylamino)butylamino)propyl)...)
Affinity DataIC50:  0.160nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50329477((S)-N-(3-(4-(3-aminopropylamino)butylamino)propyl)...)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed