BDBM50329615 CHEMBL1270139::N-hydroxy-2-((3aR,6aS)-5-(naphthalen-2-ylmethyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)pyrimidine-5-carboxamide

SMILES ONC(=O)c1cnc(nc1)N1C[C@@H]2CN(Cc3ccc4ccccc4c3)C[C@@H]2C1

InChI Key InChIKey=KPGKJQJLWZJYMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329615   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50329615(N-hydroxy-2-((3aR,6aS)-5-(naphthalen-2-ylmethyl)he...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50329615(N-hydroxy-2-((3aR,6aS)-5-(naphthalen-2-ylmethyl)he...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 at 50 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed