BDBM50329771 4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide::4-{2-[N-(6-Methoxy-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide::CHEMBL1233768

SMILES COc1ncnc(NCCc2ccc(cc2)S(N)(=O)=O)c1[N+]([O-])=O

InChI Key InChIKey=ZIQFGPRCONAHFK-UHFFFAOYSA-N

Data  8 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50329771   

TargetCarbonic anhydrase 1(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  67nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  280nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  70nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCarbonic anhydrase 13(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  230nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 7(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  130nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 7(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  440nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 13(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  130nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329771(4-{2-[(6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl...)
Affinity DataKd:  150nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)