BDBM50329830 2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-yl]acetyl}benzenesulfonamide::CHEMBL1272189::N-alkylated benzimidazole derivative, 4c

SMILES NS(=O)(=O)c1cc(ccc1Cl)C(=O)Cn1c(CO)nc2ccccc12

InChI Key InChIKey=FDKWBNMTKPSTKP-UHFFFAOYSA-N

Data  9 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50329830   

TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  7.14E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  1.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  400nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 12(Human)
Vilnius University

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  5.56E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 13(Human)
Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  300nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  7.10E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  400nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 13(Human)
Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329830(2-Chloro-5-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  333nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed