BDBM50329888 2-chloro-N-(6-(4-methoxy-6-(trifluoromethyl)pyrimidin-2-yl)pyridin-3-yl)acetamide::CHEMBL1271979

SMILES COc1cc(nc(n1)-c1ccc(NC(=O)CCl)cn1)C(F)(F)F

InChI Key InChIKey=HQPHWNQQDMBMDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329888   

TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329888(2-chloro-N-(6-(4-methoxy-6-(trifluoromethyl)pyrimi...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329888(2-chloro-N-(6-(4-methoxy-6-(trifluoromethyl)pyrimi...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed