BDBM50329940 6-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methylpyrimidine-4-carboxamide Hydrochloride::CHEMBL1271816

SMILES Cc1nc(cc(n1)C(C)(C)C)C(=O)NCCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=JVJNRJFMZQRGMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329940   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329940(6-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin...)
Affinity DataIC50: 458nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329940(6-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin...)
Affinity DataIC50: 575nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329940(6-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin...)
Affinity DataIC50: 730nMAssay Description:Displacement of [3H]imipramine from human recombinant SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329940(6-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed