BDBM50329941 CHEMBL1271698::N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2,6-dimethylpyrimidine-4-carboxamide Hydrochloride

SMILES Cc1cc(nc(C)n1)C(=O)NCCCN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=IUOQUUDCQSGQGZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329941   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329941(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 166nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329941(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 289nMAssay Description:Displacement of [3H]imipramine from human recombinant SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329941(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 610nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329941(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed