BDBM50329947 CHEMBL1271984::N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-6-methyl-2-(methylthio)pyrimidine-4-carboxamide hydrochloride

SMILES CSc1nc(C)cc(n1)C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=QGSXAJBDTYUXEY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329947   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329947(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 55nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329947(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 81nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329947(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 881nMAssay Description:Displacement of [3H]imipramine from human recombinant SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed