BDBM50329949 2-tert-butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-6-methylpyrimidine-4-carboxamide hydrochloride::CHEMBL1271874

SMILES Cc1cc(nc(n1)C(C)(C)C)C(=O)NCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=CTAVSDRIGHMRCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329949   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329949(2-tert-butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin...)
Affinity DataIC50: 69nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329949(2-tert-butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin...)
Affinity DataIC50: 494nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329949(2-tert-butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin...)
Affinity DataIC50: 6.37E+3nMAssay Description:Displacement of [3H]imipramine from human recombinant SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed