BDBM50330225 CHEMBL1272004::N-[(1R)-1-Phenylethyl]-N-(5,6,7,8-tetrahydrobenzo[4,5]thieno-[2,3-d]pyrimidin-4-yl)amine

SMILES C[C@@H](Nc1ncnc2sc3CCCCc3c12)c1ccccc1

InChI Key InChIKey=XSCMNQGFHHGUOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330225   

TargetEpidermal growth factor receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330225(N-[(1R)-1-Phenylethyl]-N-(5,6,7,8-tetrahydrobenzo[...)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50330225(N-[(1R)-1-Phenylethyl]-N-(5,6,7,8-tetrahydrobenzo[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50330225(N-[(1R)-1-Phenylethyl]-N-(5,6,7,8-tetrahydrobenzo[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed