BDBM50330226 2-(5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-ylamino)-1-ethanol::CHEMBL1269735

SMILES OCCNc1ncnc2sc3CCCCc3c12

InChI Key InChIKey=ROVQPWBLPZTSHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330226   

TargetEpidermal growth factor receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330226(2-(5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50330226(2-(5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50330226(2-(5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed