BDBM50330330 CHEMBL1276020::Ethyl1-(3-(2-(1-ethoxy-1,3-dioxo-3-phenylpropan-2-ylidene)hydrazinyl)phenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate

SMILES CCOC(=O)C(=NNc1cccc(c1)-n1nc(C(=O)Nc2nnc(s2)S(N)(=O)=O)c(C(=O)OCC)c1-c1ccccc1)C(=O)c1ccccc1

InChI Key InChIKey=ALGAPFGAIHDCTQ-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50330330   

TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330330(Ethyl1-(3-(2-(1-ethoxy-1,3-dioxo-3-phenylpropan-2-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330330(Ethyl1-(3-(2-(1-ethoxy-1,3-dioxo-3-phenylpropan-2-...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330330(Ethyl1-(3-(2-(1-ethoxy-1,3-dioxo-3-phenylpropan-2-...)
Affinity DataKi:  2.17E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330330(Ethyl1-(3-(2-(1-ethoxy-1,3-dioxo-3-phenylpropan-2-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330330(Ethyl1-(3-(2-(1-ethoxy-1,3-dioxo-3-phenylpropan-2-...)
Affinity DataKi:  5.92E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330330(Ethyl1-(3-(2-(1-ethoxy-1,3-dioxo-3-phenylpropan-2-...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed