BDBM50330337 CHEMBL1276394::Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate

SMILES CCOC(=O)c1c(nn(c1-c1ccccc1)-c1cccc(I)c1)C(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=CTOWPVTYZJLDOC-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50330337   

TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330337(Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330337(Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330337(Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,...)
Affinity DataKi:  70nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330337(Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,...)
Affinity DataKi:  90nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330337(Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human carbonic anhydrase 1 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330337(Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human carbonic anhydrase 2 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed