BDBM50330338 CHEMBL1276017::Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl)phenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate

SMILES [#6]-[#6]-[#8]-[#6](=O)-c1c(nn(c1-c1ccccc1)-c1cccc(-[#7]\[#7]=[#6](/[#6](-[#6])=O)-[#6](-[#6])=O)c1)-[#6](=O)-[#7]-c1nnc(s1)S([#7])(=O)=O

InChI Key InChIKey=OGQNQIABDFPBAB-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50330338   

TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl...)
Affinity DataKi:  170nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human carbonic anhydrase 2 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl...)
Affinity DataKi:  250nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human carbonic anhydrase 1 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330338(Ethyl1-(3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed