BDBM50330522 1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1277837

SMILES CC(C)n1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=YKEFFXDXDCCGLC-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50330522   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi:  1.08E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2C receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi:  2.04E+3nMAssay Description:Displacement of [3H]LSD from human cloned dopamine D2 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1B receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1D receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned alpha2A adrenergic receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataIC50:  2.90nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed