BDBM50330533 5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-indazole::CHEMBL1277917

SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=SVLOBFJUUCMSOY-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50330533   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  355nMAssay Description:Displacement of [3H]LSD from human cloned dopamine D2 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  753nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  978nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  3.07E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2C receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1B receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1D receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned alpha2A adrenergic receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataIC50:  8.80nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed