BDBM50330707 4,5-dimethyl-2-(5-(4-methylpiperazin-1-ylsulfonyl)pyridin-2-yl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1277931

SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(nc1)-n1[nH]c2cc(=O)n(C)c(C)c2c1=O

InChI Key InChIKey=RTHIKBFTYSTIHR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330707   

TargetNADPH oxidase 4(Human)
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330707(4,5-dimethyl-2-(5-(4-methylpiperazin-1-ylsulfonyl)...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed