BDBM50330715 2-(2-chlorophenyl)-5-(3-hydroxypropyl)-4-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1278110

SMILES Cc1n(CCCO)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12

InChI Key InChIKey=VQXIMZFSMHXQNT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330715   

TargetNADPH oxidase 4(Human)
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330715(2-(2-chlorophenyl)-5-(3-hydroxypropyl)-4-methyl-1H...)
Affinity DataKi:  565nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed