BDBM50330717 2-(2-chlorophenyl)-4-methyl-5-(4-(4-methylpiperazin-1-yl)-4-oxobutyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1278199

SMILES CN1CCN(CC1)C(=O)CCCn1c(C)c2c(cc1=O)[nH]n(-c1ccccc1Cl)c2=O

InChI Key InChIKey=YYWQXACDBDCTHO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330717   

TargetNADPH oxidase 4(Human)
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330717(2-(2-chlorophenyl)-4-methyl-5-(4-(4-methylpiperazi...)
Affinity DataKi:  428nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed