BDBM50330720 2-(2-chlorophenyl)-4-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)benzyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1276858

SMILES CN1CCN(Cc2ccc(Cn3c(C)c4c(cc3=O)[nH]n(-c3ccccc3Cl)c4=O)cc2)CC1

InChI Key InChIKey=AFZWIYFEICOZIA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330720   

TargetNADPH oxidase 4(Human)
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330720(2-(2-chlorophenyl)-4-methyl-5-(4-((4-methylpiperaz...)
Affinity DataKi:  515nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed