BDBM50330724 2,4-dimethyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1276223

SMILES Cc1n(Cc2ccccn2)c(=O)cc2[nH]n(C)c(=O)c12

InChI Key InChIKey=POESYHVFWKJJEZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330724   

TargetNADPH oxidase 4(Human)
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330724(2,4-dimethyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,...)
Affinity DataKi:  387nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed