BDBM50330866 CHEMBL1277420::trans rac-N1-(4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)-N2-(4-fluorobenzyl)ethane-1,2-diamine

SMILES Cc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCc2ccc(F)cc2)c1

InChI Key InChIKey=SUEOVVVPGSQYAH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330866   

TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330866(trans rac-N1-(4-((6-amino-4-methylpyridin-2-yl)met...)
Affinity DataKi:  870nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330866(trans rac-N1-(4-((6-amino-4-methylpyridin-2-yl)met...)
Affinity DataKi:  2.74E+4nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330866(trans rac-N1-(4-((6-amino-4-methylpyridin-2-yl)met...)
Affinity DataKi:  7.88E+4nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed