BDBM50330910 7-(4-fluoro-2-((1R,4R)-2-methyl-2-azabicyclo[2.2.1]heptan-5-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine::CHEMBL1276182

SMILES CN1C[C@@H]2C[C@H]1CC2c1cc(F)ccc1-c1ccnc2c(c(nn12)-c1ccncc1)-c1cccc2[nH]ncc12

InChI Key InChIKey=TUDBQXAJQWDULL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330910   

TargetSerine/threonine-protein kinase B-raf(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330910(7-(4-fluoro-2-((1R,4R)-2-methyl-2-azabicyclo[2.2.1...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BRAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed