BDBM50331001 (5-(4-hydroxy-3-(trifluoromethyl)phenyl)thiophen-2-yl)(3-hydroxyphenyl)methanone::CHEMBL1277710

SMILES Oc1cccc(c1)C(=O)c1ccc(s1)-c1ccc(O)c(c1)C(F)(F)F

InChI Key InChIKey=KEJQMTAEAKWJLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331001   

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331001((5-(4-hydroxy-3-(trifluoromethyl)phenyl)thiophen-2...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331001((5-(4-hydroxy-3-(trifluoromethyl)phenyl)thiophen-2...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed